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东部战区总医院骨科
骨肿瘤腰椎间盘突出骨折脊柱肿瘤骨巨细胞瘤人工关节置换术膝关节损伤骨坏死手外伤
脊柱退行性疾病,脊柱及四肢原发及转移性肿瘤的诊治,复杂骨折等疾病的诊治。
周光新,南京军区南京总医院骨科副主任医师,医学博士,博士后。骨科主任助理,南京大学、东南大学、南京医科大学、南方医科大学硕士生导师;全军骨科青年委员会副主任委员,全军骨科青年委员会脊柱学组副主任委员,中国抗癌协会肉瘤委员会委员,中华医学会骨科分会骨肿瘤学组青年委员,全军骨科专业委员会骨肿瘤学组委员兼秘书,中国抗癌协会骨瘤委员会骨盆肿瘤学组委员,江苏省骨科专业委员会青年委员,江苏省骨科专业委员会骨肿瘤学组委员兼秘书,南京军区骨肿瘤学组委员,享受军队优秀科技人才津贴,江苏省“六大人才高峰”高层次人才培养对象,江苏省“333”高层次人才培养对象。主持国家自然科学基金两项、全国博士后面上基金、江苏省自然科学基金面上项目,全军青年科技项目各一项,第二完成人申请江苏省自然基金及军区基金各一项。2008年赴德国法兰克福风湿病中心及汉堡ENDO CLINIC医院进修。2015年被中国骨科医师协会评为“先进工作者”,获军队科技进步二等奖及江苏省科技进步三等奖各一项,获“刘志红青年医学奖”二次,获三等功一次。在SCI及核心期刊发表论文多篇。 主持的基金项目 国家自然科学基金面上项目 (81472508) 国家自然科学基金青年项目 (81102039) 国家博士后自然科学基金面上项目 (2012M512178) 江苏省六大人才高峰项目 (2014-WSW-042) 江苏省自然科学基金面上项目 (BK20141376) 全军青年科技项目 (19QNP038) 发表的论文: 1.Expression profiles of miRNAs in giant cell tumor of bone showed miR-187-5p and miR-1323 can regulate biological functions through inhibiting FRS2. Cancer Med. 2020 May;9(9):3163-3173. 2. Functions of Exogenous RUNX2 in Giant Cell Tumor of Bone In Vitro. Orthop Surg. 2020 Apr;12(2):668-678. 3. MiR-139 inhibits osteosarcoma cell proliferation and invasion by targeting ROCK1. Front Biosci (Landmark Ed). 2019 Jun 1;24:1167-1177. 4. Association between Mediterranean diet adherence and colorectal cancer: a dose-response meta-analysis. Am J Clin Nutr. 2020 May 2. 5. Efficacy Analysis of Separation Surgery Combined with SBRT for Spinal Metastases-A Long-Term Follow-Up Study Based on Patients with Spinal Metastatic Tumor in a Single-Center. Orthop Surg. 2020 Apr;12(2):404-420. 6.Ling Z, Fan G, Yao D, Zhao J, Zhou Y, Feng J, Zhou G, Chen Y. MicroRNA-150 functions as a tumor suppressor and sensitizes osteosarcoma to doxorubicin-induced apoptosis by targeting RUNX2. Exp Ther Med. 2020 Jan;19(1):481-488. 7.MiR-29b suppresses the proliferation and migration of osteosarcoma cells by targeting CDK6.Protein Cell. 2016 May 26. 8.Identification of miR-199a-5p in serum as noninvasive biomarkers for detecting and monitoring osteosarcoma. Tumour Biol. 2015 Jun 12. 9.miR-16 promotes the apoptosis of human cancer cells by targeting FEAT.BMC Cancer. 2015 Jun 2;15:448. 10. Preparation and antitumor activity of a polymer derivative of metrotrexate. The American Joournal of the Medical Sciences.(2012 Oct;344(4):294-9) 11.A microRNA expression signature predicts meningioma recurrence. International Journal of Cancer. (2013 Jan 1;132(1):128-36 12. MicroRNAs in osteosarcoma: from biological players to clinical contributors. The Journal of International Medical Research (2013 Feb;41(1):1-12) 13.Composite Reconstruction of the Hip Following Resection of Periacetabular Tumors: Middle-Term Outcome. J Arthroplasty. 2013 Mar;28(3):537-42. 14.DNA/chitosan nanocomplex as a novel drug carrier for doxorubicin.Drug Deliv. 2009 Apr;16(3):135-44. 15.The canonical Wnt-beta-catenin pathway in development and chemotherapy of osteosarcoma. Front Biosci. 2013 Jun 1;18:1384-91.